[HTML][HTML] From bedside to bench-in vivo and in vitro evaluation of mechanically assisted cough treatment in a patient with bulbar amyotrophic lateral sclerosis
T Andersen, O Fondenes, OD Røksund… - Respiratory Medicine …, 2022 - Elsevier
… with Amyotrophic Lateral Sclerosis, the … Amyotrophic Lateral Sclerosis experienced that
treatment with MI-E was exhausting and inefficient. Despite adjustments of settings, all treatment …
treatment with MI-E was exhausting and inefficient. Despite adjustments of settings, all treatment …
[HTML][HTML] A perspective on therapies for amyotrophic lateral sclerosis: can disease progression be curbed?
X Xu, D Shen, Y Gao, Q Zhou, Y Ni, H Meng… - Translational …, 2021 - Springer
… treatment of spasticity in ALS patients, as they can control spasticity with safety and efficacy
in multiple sclerosis [58… cohort study has revealed high treatment satisfaction with nabiximols, …
in multiple sclerosis [58… cohort study has revealed high treatment satisfaction with nabiximols, …
[HTML][HTML] Inosine in neurodegenerative diseases: From the bench to the bedside
MS Basile, P Bramanti, E Mazzon - Molecules, 2022 - mdpi.com
… its safety and efficacy and its use as a complementary therapy along with other approved
drugs. … Urate levels predict survival in amyotrophic lateral sclerosis: Analysis of the expanded …
drugs. … Urate levels predict survival in amyotrophic lateral sclerosis: Analysis of the expanded …
Therapeutic approaches to amyotrophic lateral sclerosis from the lab to the clinic
… Amyotrophic Lateral Sclerosis (ALS) is a neurodegenerative disease that affects adults and
… from bench to bedside in the field of ALS treatment. More than 160 drug candidates or ther…
… from bench to bedside in the field of ALS treatment. More than 160 drug candidates or ther…
[HTML][HTML] Translational study for amyotrophic lateral sclerosis treatment
S Schröder, G Litscher, W Pan - Frontiers in Neurology, 2023 - frontiersin.org
Amyotrophic lateral sclerosis (ALS) is a motor neuron disease characterized by progressive
loss of upper and lower motor neurons. Despite significant scientific efforts in the last …
loss of upper and lower motor neurons. Despite significant scientific efforts in the last …
[HTML][HTML] Neuroimaging findings in preclinical amyotrophic lateral sclerosis models—How well do they mimic the clinical phenotype? A systematic review
AE Cannon, WE Zürrer, C Zejlon, Z Kulcsar… - Frontiers in Veterinary …, 2023 - frontiersin.org
… This opposes the high attrition of drugs during bench-to-bedside translation … drug development.
These findings emphasize a careful application of these model systems for ALS therapy …
These findings emphasize a careful application of these model systems for ALS therapy …
Silence superoxide dismutase 1 (SOD1): a promising therapeutic target for amyotrophic lateral sclerosis (ALS)
E Abati, N Bresolin, G Comi, S Corti - Expert opinion on therapeutic …, 2020 - Taylor & Francis
… the small study sample and the low treatment doses received by patients. Another silencing
… RNAi therapy from the bench to the bedside is the lack of an in vivo biomarker of therapeutic …
… RNAi therapy from the bench to the bedside is the lack of an in vivo biomarker of therapeutic …
[HTML][HTML] Stathmin 2 is a potential treatment target for TDP-43 proteinopathy in amyotrophic lateral sclerosis
Y Liu, D Yan, L Yang, X Chen, C Hu… - Translational …, 2024 - Springer
… could be a barrier to axonal outgrowth/regeneration during patient treatment. Despite the
gap from bench to bedside, STMN2 is a potential therapeutic target for TDP-43 proteinopathy. …
gap from bench to bedside, STMN2 is a potential therapeutic target for TDP-43 proteinopathy. …
[HTML][HTML] Therapeutics for neurodegenerative diseases by targeting the gut microbiome: from bench to bedside
YY Ma, X Li, JT Yu, YJ Wang - Translational Neurodegeneration, 2024 - Springer
… ), Parkinson’s disease (PD), amyotrophic lateral sclerosis (ALS) and Huntington’s disease
(… and treatments that can reshape the gut microbiome, serving as potential therapies for NDs (…
(… and treatments that can reshape the gut microbiome, serving as potential therapies for NDs (…
[HTML][HTML] Organ on a chip: a novel in vitro biomimetic strategy in amyotrophic lateral sclerosis (ALS) modeling
B Arjmand, S Kokabi Hamidpour, Z Rabbani… - Frontiers in …, 2022 - frontiersin.org
… treatment has been found for amyotrophic lateral sclerosis (… the disease, multiple medical
therapies have been proposed … translational researches from bench to bedside in various …
therapies have been proposed … translational researches from bench to bedside in various …